I am running the latest version of Adobe Acrobat Pro DC and macOS Mojave and have never seen these issues alleviated by two years of updates. My computer is a relatively powerful: 2016 15-inch MacBook Pro connected to an eGPU with Radeon RX 580 and an LG 4K monitor (more than enough power to edit PDFs).
I have tried deleting the prefernce files outlined in other topics, which did nothing to alleviate the issue at all. It appears to be very poorly optimized compared to other professional software titles which all run smoothly on macOS: Word, Excel, Pages, Numbers, etc. This happens no matter what the size of the PDF is from less than 1 MB to 10+ MB. For the last two years I have had consistent problems with Acrobat Pro DC being extremely slow/stuttery while scrolling, highlighting, commenting on a document.
